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Synthesis, Biological, and Immunological Properties of Cyclic Peptides from Plasmodium Falciparum Merozoite Surface Protein-1

✍ Scribed by Eduardo Lioy; Jorge Suarez; Fanny Guzmàn; Sibylle Siegrist; Gerd Pluschke; Manuel E. Patarroyo

Publisher: John Wiley and Sons
Year: 2001
Tongue: English
Weight: 120 KB
Volume: 113
Category: Article
ISSN: 0044-8249
DOI: 10.1002/1521-3757(20010716)113:14<2701::aid-ange2701>3.0.co;2-8

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## Abstract The __Plasmodium falciparum__ merozoite surface protein‐1 19 kDa fragment (MSP‐1~19~) comprises two closely packed EGF‐like domains (EGF=epidermal growth factor), each stabilized by three disulfide bonds. The native conformation of this protein is important for eliciting __P. falciparum