𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis, Bioactivity, and Cloning of the L-Type Calcium Channel Blocker ω-Conotoxin TxVII †

✍ Scribed by Sasaki, Toru; Feng, Zhong-Ping; Scott, Randolph; Grigoriev, Nikita; Syed, Naweed I.; Fainzilber, Michael; Sato, Kazuki

Book ID
127383684
Publisher
American Chemical Society
Year
1999
Tongue
English
Weight
113 KB
Volume
38
Category
Article
ISSN
0006-2960

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Preparation and Characterization of Biot
Preparation and Characterization of Biotinylated Analogs of the Calcium Channel Blocker ω-Conotoxin
✍ O.T. Jones; A.P. So 📂 Article 📅 1993 🏛 Elsevier Science 🌐 English ⚖ 486 KB

We have prepared a series of biotinylated analogs of \(\omega\)-conotoxin ( \(\omega \mathrm{CgTx}\) ) as potent, selective markers for \(\mathrm{N}-\) type calcium channels. At \(\mathbf{p H} 9.5\), reaction of \(\omega \mathrm{CgTx}\) with amidocaproylbiotin succinimidyl ester gives three biotinyl

Solid-phase Synthesis of ω-Agatoxin IVA,
Solid-phase Synthesis of ω-Agatoxin IVA, a P-type Calcium Channel Blocker
✍ Jamila Najib; Thierry Letailleur; Jean-Claude Gesquière; André Tartar 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 700 KB

omega-Agatoxin IVA, isolated from the venom of funnel web spider Agelenopsis aperta, blocks potently and selectively P-type calcium channels. This toxin, composed of 48 amino acids and containing 8 cysteine residues, was synthesized by the solid-phase procedure. The Cys residues were protected by ac