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Synthesis and α-Mannosidase Inhibitory Activity of Three Deoxy Derivatives of Mannostatin A

✍ Scribed by Seiichiro Ogawa; Takayuki Morikawa


Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
313 KB
Volume
2000
Category
Article
ISSN
1434-193X

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✦ Synopsis


Three deoxy derivatives 2-4 of the α-mannosidase inhibitor mannostatin A (1) were synthesized, and their inhibition of Jack bean α-mannosidase was evaluated in order to elucidate the roles of each of the three hydroxyl groups of the inhibitor. The 1-and 2-deoxy derivatives 2 and 3 retained some


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The numbers in the list of PDB files associated with this paper are incorrect. The ID codes should be 3DX0, 3DX1, 3DX2, 3DX3 and 3DX4.