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Synthesis and study of reversible acetylcholinesterase inhibitors.

✍ Scribed by M. L. Aleksandrova; N. S. Androsov; D. V. Ioffe; A. N. Panyukov


Book ID
112407851
Publisher
Springer
Year
1978
Tongue
English
Weight
273 KB
Volume
12
Category
Article
ISSN
0091-150X

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Synthesis of Reversible Inhibitors of Ac
✍ Peter Thanei-Wyss; Peter G. Waser πŸ“‚ Article πŸ“… 1983 πŸ› John Wiley and Sons 🌐 German βš– 485 KB

## Abstract The synthesis and characterization of some reversible acetylcholinesterase inhibitors are described in detail. They are structurally related to the natural substrate acetylcholine. All of them bear a trimethylammonium moiety as β€˜cationic head’. Instead of an electrophilic ester group, t