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Synthesis and study of opioid activity of modified analogues of DAla2, DLeu2-enkephalin

✍ Scribed by M. M. Sobirov; Sh. Kh. Khalikov; S. V. Zaitsev; S. S. Saidov; S. D. Varfolomeev

Book ID
104828611
Publisher
Springer
Year
1989
Tongue
English
Weight
141 KB
Volume
25
Category
Article
ISSN
0009-3130

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## Abstract The synthesis and biological testing of analogues of Met‐enkephalin, a recently discovered opioid peptide from mammalian brain, are described. Testing involved determination of affinity constants for an opiate receptor site and of analgesic potency in the tail‐flick test in mouse. The e