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Synthesis and study of a fragment (584–618) of the transmembrane protein gp41 HIV-I

✍ Scribed by Alia Yu. Rubina; Zhanna D. Bespalova; Mikhail V. Ovchinikov; Valerii N. Bushuev; Elena B. Popletaeva; Eugenii E. Efremov

Book ID
111729844
Publisher
Royal Society of Chemistry
Year
1996
Tongue
English
Weight
200 KB
Volume
6
Category
Article
ISSN
0959-9436

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Conformational study of fragments of env
Conformational study of fragments of envelope proteins (gp120: 254–274 and gp41: 519–541) of HIV-1 by NMR and MD simulations
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## Abstract The envelope proteins, gp120 and gp41 of HIV‐1, play a crucial role in receptor (CD4^+^ lymphocytes) binding and membrane fusion. The fragment 254–274 of gp120 is conserved in all strains of HIV and, as a part of the full gp120 protein, behaves as ‘immunosilent’, but as an individual fr