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Synthesis and structure–activity relationships of harmine derivatives as potential antitumor agents

✍ Scribed by Cao, Rihui; Fan, Wenxi; Guo, Liang; Ma, Qin; Zhang, Guoxian; Li, Jianru; Chen, Xuemei; Ren, Zhenghua; Qiu, Liqin


Book ID
119952252
Publisher
Elsevier Science
Year
2013
Tongue
French
Weight
256 KB
Volume
60
Category
Article
ISSN
0223-5234

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## Abstract Beta‐carboline alkaloids such as harmine are present in medicinal plants such as __Peganum harmala__ that have been used as folk medicine in anticancer therapy. In our study, 9 harmine derivatives (including harmine) were investigated for their antitumor effects and acute toxicities in