Synthesis and cytotoxic evaluation of ci
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Magali Lorion; Vangelis Agouridas; Axel Couture; Eric Deniau; Pierre Grandclaudo
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Article
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2010
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Elsevier Science
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French
⚖ 460 KB
A series of cis-locked stilbenic compounds related to combretastatin and combretastatin A4 has been designed and synthesized. The cytotoxic effects of these rigid analogues were evaluated as well as their abilities to inhibit tubulin polymerization.