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Synthesis and structure–activity relationship of 3-phenyl-3H-quinazolin-4-one derivatives as CXCR3 chemokine receptor antagonists

✍ Scribed by Stefania Storelli; Pauline Verdijk; Dennis Verzijl; Henk Timmerman; Andrea C. van de Stolpe; Cornelis P. Tensen; Martine J. Smit; Iwan J.P. De Esch; Rob Leurs

Book ID
108073627
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
214 KB
Volume
15
Category
Article
ISSN
0960-894X

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📜 SIMILAR VOLUMES

Synthesis and Structure—Activity Relatio
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✍ Stefania Storelli; Dennis Verzijl; Jawad Al-Badie; Niels Elders; Leontien Bosch; 📂 Article 📅 2007 🏛 John Wiley and Sons ⚖ 30 KB 👁 2 views

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Synthesis and Antiproliferative Activity
Synthesis and Antiproliferative Activity of Novel 3-(Indazol-3-yl)-quinazolin-4(3H)-one and 3-(Indazol-3-yl)-benzotriazin-4(3H)-one Derivatives
✍ Demetrio Raffa; Giuseppe Daidone; Benedetta Maggio; Domenico Schillaci; Fabiana 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 42 KB 👁 2 views

Several new 3-(indazol-3-yl)-quinazolin-4(3H)-one and 3-(indazol-3-yl)-benzotriazin-4(3H)-one derivatives 5 and 6 were synthesized and tested for their in vitro antiproliferative activity against Raji, K562, and K562-R cell lines. The pharmacological screening showed that some 2, 6, or 7-substituted