✦ LIBER ✦

Synthesis and Structure−Activity Relationship in a Class of Indolebutylpiperazines as Dual 5-HT1A Receptor Agonists and Serotonin Reuptake Inhibitors

✍ Scribed by Heinrich, Timo; Böttcher, Henning; Gericke, Rolf; Bartoszyk, Gerd D.; Anzali, Soheila; Seyfried, Christoph A.; Greiner, Hartmut E.; van Amsterdam, Christoph

Book ID: 115498248
Publisher: American Chemical Society
Year: 2004
Tongue: English
Weight: 204 KB
Volume: 47
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm040793q

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Design, synthesis, and pharmacological e

Design, synthesis, and pharmacological evaluation of azetedine and pyrrolidine derivatives as dual norepinephrine reuptake inhibitors and 5-HT1A partial agonists

✍ Martin Pettersson; Brian M. Campbell; Amy B. Dounay; David L. Gray; Longfei Xie; 📂 Article 📅 2011 🏛 Elsevier Science 🌐 English ⚖ 718 KB

Compounds with combined norepinephrine reuptake inhibitor (NRI) and serotonin 1A (5-HT 1A ) partial agonist pharmacology may offer a new therapeutic approach for treating symptoms of neuropsychiatric disorders including ADHD, depression, and anxiety. Herein we describe the design and optimization of

ChemInform Abstract: Design, Synthesis,

ChemInform Abstract: Design, Synthesis, and Pharmacological Evaluation of Azetedine and Pyrrolidine Derivatives as Dual Norepinephrine Reuptake Inhibitors and 5-HT1A Partial Agonists.

✍ Martin Pettersson; et al. et al. 📂 Article 📅 2011 🏛 John Wiley and Sons ⚖ 34 KB 👁 2 views

Antagonists of serotonin 5-HT6receptors.

Antagonists of serotonin 5-HT6receptors. III. Pyridine-substituted 3-(phenylsulfonyl)pyrazolo[1,5-a]pyrimidines: synthesis and structure – activity relationship

✍ Ivashchenko, A. V.; Golovina, E. S.; Kadieva, M. G.; Kysil, V. M.; Mitkin, O. D. 📂 Article 📅 2012 🏛 Springer 🌐 English ⚖ 117 KB

ChemInform Abstract: Synthesis and Struc

ChemInform Abstract: Synthesis and Structure-Activity Relationships of 5-Substituted Tryptamine Derivatives of o-Tolylpiperazine as Agonists at 5-HT1D Receptors.

✍ M. PEREZ; P. J. PAUWELS; C. PALMIER; G. W. JOHN; J. P. VALENTIN; S. HALAZY 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 32 KB

The anxiolytic serotonin 5-HT1A receptor

The anxiolytic serotonin 5-HT1A receptor agonists buspirone, ipsapirone and gepirone are inhibitors of tyrosine hydroxylation in rat striatum

✍ Elizabeth Anne Johnson; Julia Lynn Fox; Albert J. Azzaro 📂 Article 📅 1995 🏛 Elsevier Science 🌐 English ⚖ 401 KB

Blockade of serotonin 5-HT1Band 5-HT2Are

Blockade of serotonin 5-HT1Band 5-HT2Areceptors suppresses the induction of locomotor activity by 5-HT reuptake inhibitors, citalopram and fluvoxamine, in NMRI mice exposed to a novel environment: a comparison to other 5-HT receptor subtypes

✍ Mark J. Millan; Sylvie Veiga; Sylvie Girardon; Mauricette Brocco 📂 Article 📅 2003 🏛 Springer 🌐 English ⚖ 300 KB