Synthesis and structure of some condensed quinazolines

✍ Scribed by Badawy, Mohamed A. ;Abdel-Hady, Sayed A. ;Mahmoud, Ahmed H. ;Ibrahim, Yehia A.

• Publisher: John Wiley and Sons
• Year: 1990
• Tongue: English
• Weight: 242 KB
• Volume: 1990
• Category: Article
• ISSN: 0947-3440
• DOI: 10.1002/jlac.1990199001151

✦ Synopsis

Abstract

Condensation of 2‐hydrazino‐4(3__H__)‐quinazolinone (1) with bielectrophilic reagents gives the corresponding triazoloquinazolines 8, the structures of which were established by selective synthesis through deamination of their N‐amino derivatives. The synthesis of methyl‐substituted derivatives of these angular tricyclic systems and their linear isomers was also achieved starting with 3‐methyl‐ and 1‐methyl‐2‐hydrazino‐quinazolinone.