✦ LIBER ✦

Synthesis and structure of cycloalkane- and norbornane-condensed 6-aryl-1,2,4,5-tetrahydropyridazinones

✍ Scribed by Ferenc Csende; Anasztárzia Hetényi; Géza Stájer; Ferenc Fülöp

Publisher: Journal of Heterocyclic Chemistry
Year: 2004
Tongue: English
Weight: 220 KB
Volume: 41
Category: Article
ISSN: 0022-152X
DOI: 10.1002/jhet.5570410217

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

The C=N double bond of certain cis‐ or trans‐cycloalkane and diexo‐ or diendo‐norbornane‐condensed pyridazinones was reduced with NaBH~3~CN. The cis‐ or trans nature of the starting cycloalkane derivatives was always retained in the saturated products, with a high degree of diastereoselectivity: the hydrogen on the new stereocenter and the annelational hydrogen next to the carbonyl always exhibited the same steric orientation. The stereostructures were determined by means of nmr measurements and confirmed by molecular modelling.

📜 SIMILAR VOLUMES

Synthesis and Structure of Cycloalkane-

Synthesis and Structure of Cycloalkane- and Norbornane-Condensed 6-Aryl-1,2,4,5-tetrahydropyridazinones.

✍ Ferenc Csende; Anasztazia Hetenyi; Geza Stajer; Ferenc Fueloep 📂 Article 📅 2004 🏛 John Wiley and Sons ⚖ 99 KB

Synthesis and properties of 1-aryl-2-alk

Synthesis and properties of 1-aryl-2-alkyl-1,4,5,6-tetrahydropyrimidines

✍ Liliana R. Orelli; Fernando Niemevz; María B. García; Isabel A. Perillo 📂 Article 📅 1999 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 543 KB

## Abstract A general method is described for the synthesis of 1‐aryl‐2‐alkyl‐1,4,5,6‐tetrahydropyrimidines 1, by cyclization of __N__‐acyl‐__N__′‐aryltrimethylenediamines 2 with trimethylsilyl polyphosphate. Precursors 2 were obtained by aminolysis of the corresponding __N__‐(3‐bromopropyl)amides

ChemInform Abstract: Synthesis of 1-Aryl

ChemInform Abstract: Synthesis of 1-Aryl-1,4,5,6-tetrahydropyrimidines and 1-Aryl-3-substituted 1,4,5,6-Tetrahydropyrimidinium Salts.

✍ Liliana R. Orelli; Maria B. Garcia; Isabel A. Perillo 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 28 KB 👁 1 views

Synthesis and Structure of 5-Indolyl-6-t

Synthesis and Structure of 5-Indolyl-6-thienyl-1,2,4-triazines.

✍ M. M. Krayushkin; V. N. Yarovenko; I. P. Sedishev; I. V. Zavarzin; L. G. Voronts 📂 Article 📅 2006 🏛 John Wiley and Sons ⚖ 21 KB 👁 1 views

ChemInform Abstract: Synthesis and Prope

ChemInform Abstract: Synthesis and Properties of 1-Aryl-2-alkyl-1,4,5,6-tetrahydropyrimidines.

✍ Liliana R. Orelli; Fernando Niemevz; Maria B. Garcia; Isabel A. Perillo 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 29 KB 👁 1 views

Synthesis and Structure of a 1,2,5,6-Tet

Synthesis and Structure of a 1,2,5,6-Tetrahydro-1,2,5,6-tetraborocine

✍ Dipl.-Chem. Albrecht Krämer; Dr. Hans Pritzkow; Prof. Dr. Walter Siebert 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 English ⚖ 237 KB 👁 2 views