Synthesis and Structure of 5-Methoxy-6,7-methylenedioxyflavone
✍ Scribed by Ng, A. S.; Goh, W. P.
- Book ID
- 121388155
- Publisher
- American Chemical Society
- Year
- 1990
- Tongue
- English
- Weight
- 204 KB
- Volume
- 53
- Category
- Article
- ISSN
- 0163-3864
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📜 SIMILAR VOLUMES
The title compound, C 17 H 12 O 6 , forms an infinite onedimensional zigzag-like chain developing parallel to the b axis through O-HÁ Á ÁO hydrogen bonds. The chains are stacked along the c axis. The crystal structure is further stabilized by weakand C-HÁ Á Á interactions.
A novel Mannich type condensation between the monomethyl ester of acetonedicarboxylic acid, methylamine hydrochloride, and hydrolyzed dimethoxydihydrothran gave 6-or 7-functionalized flketo ester tropanes 12 -15. Further elaboration afforded a series of 6-or 7-hydroxy and 6-or 7methoxy 21~-methoxyca