Synthesis and Structure of 2,2′-Spirobi(1,3-benzodioxole) Derivative Prepared from 3,5-Di(tert-butyl)-1,2-benzoquinone.
✍ Scribed by V. N. Komissarov; Yu. A. Sayapin; V. I. Minkin; V. V. Tkachev; S. M. Aldoshin; G. V. Shilov
- Publisher
- John Wiley and Sons
- Year
- 2007
- Weight
- 16 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0931-7597
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✦ Synopsis
Abstract
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## Abstract Both enantiomers of 2‐__tert__‐butyl‐2‐methyl‐1,3‐benzodioxole‐4‐carboxylic (TBMB) acid, which has a unique quaternary chiral center located on the acetal carbon, were prepared from a racemic ketone in which the carboxy group was replaced by a trifluoroacetyl group. First, reduction wit