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Synthesis and structure-activity relationship of 2,5-diaryltetrahydrofurans as PAF antagonists

✍ Scribed by T. Biftu; J.C. Chabala; J. Acton; T. Beattie; D. Brooker; R. Bugianesi; M.N. Chang; P.C. Chiang; N. Gable; N. Girotra; D. Graham; C.H. Kuo; M. Ponpipom; S. Sahoo; T.Y. Shen; K.L. Thompson; S.S. Yang; S.-B. Hwang; T. Doebber


Book ID
119050908
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
49 KB
Volume
35
Category
Article
ISSN
0090-6980

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Synthesis and structure-activity relatio
✍ Yong-Chul Kim; Emidio Camaioni; Airat U. Ziganshin; Xiao-duo Ji; Brian F. King; πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 291 KB πŸ‘ 2 views

Novel analogs of the P2 receptor antagonist pyridoxal-5β€²-phosphate-6-phenylazo-2β€²,4β€²disulfonate (PPADS) were synthesized. Modifications were made through functional group substitution on the sulfophenyl ring and at the phosphate moiety through the inclusion of phosphonates, demonstrating that a phos