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Synthesis and structural study of new highly lipophilic 1,4-dihydropyridines

✍ Scribed by Suárez, Margarita; de Armas, Merly; Ramírez, Oney; Alvarez, Amaury; Martínez-Alvarez, Roberto; Molero, Dolores; Seoane, Carlos; Liz, Ramón; de Armas, Hector Novoa; Blaton, Norbert M.; Peeters, Oswald M.; Martín, Nazario

Book ID
120510092
Publisher
Royal Society of Chemistry
Year
2005
Tongue
English
Weight
747 KB
Volume
29
Category
Article
ISSN
1144-0546

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Synthesis and structure of quinoxaline-s
Synthesis and structure of quinoxaline-substituted 1,4-dihydropyridines
✍ G. Stumm; H.-J. Niclas; G. Winter; G. Reck 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 539 KB

## Abstract The preparation of a novel series of quinoxaline‐substituted 1,4‐dihydropyridines is described. Thus, the reaction of 1 with acetoacetates in the presence of ammonia leads to dialkyl 2,6‐dimethyl‐4‐(quinoxaline‐1,4‐dioxid‐2‐yl)‐1,4‐dihydropyridine‐3,5‐dicarboxylates 2a‐g. Compounds 4a‐c