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Synthesis and Steric Structure of H-Leu-His-Lys-Leu-Gln-Thr-NH2and H-Ala-D-Ala-Lys-Leu-Ala-Thr-NH2Peptides

✍ Scribed by I. V. Rogachevskii; S. V. Burov; B. F. Shchegolev


Book ID
106522780
Publisher
Springer
Year
2005
Tongue
English
Weight
157 KB
Volume
75
Category
Article
ISSN
1070-3632

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N-1 and N-2 positional effects in the pr
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The N-1 Ala 2 and N-2 Gly 3 positional amino acids in the type II 0 turn templated 3 10 helix Boc-(D)Glu 1 -Ala 2 -Gly 3 -Lys 4 -NHMe (1) and Boc-(D)Glu 1 -Ala 2 -Gly 3 -Lys 4 -Ala 5 -Leu 6 -OMe (3) are substituted with Pro 2 and Ala 3 to obtain its variants Boc-(D)Glu 1 -Pro 2 -Ala 3 -Lys 4 -NHMe (