## Abstract Treatment of dihydrocodeinone (thio)semicarbazones 1a–d with Ac~2~O/ZnCl~2~ afforded (6__S__)‐spiro[morphinan‐6,2′(3′__H__)‐[1,3,4]oxadiazolines] (2a, b) and (6__R__)‐spiro[morphinan‐6,2′‐(3′__H__)‐[1,3,4]thiadiazolines] (3a, b), respectively. The structure of the products including the
✦ LIBER ✦
Synthesis and stereostructure of some 5,5′-disubstituted 3-acetyl-2,2′-BI-2H-1,3,4-oxa(thia)diazolines
✍ Scribed by László Somogyi; Mátyás Czugler; Pál Sohár
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- French
- Weight
- 701 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0040-4020
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✦ Synopsis
The synrhesis of some (methyf)glyoxal 1,2-bis(cxylhydrazones) (1,3-6) and their cyclization into the title compounds (7-10) under acetylating conditions p-e descriged. The stereostructures of the new bi-heterocyclic diastcrcomers were studied by H-and I C-NMR measurements as well as by X-ray anulysis.
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