Linalool was cyclized in aqueous solvents with Hg(ll) salts, thereby iridanediols were formed in -55% yield with -85% stereoselectivity, favoring the cis, trans-isomer 2. Utilizing the reaction, cyclonerodiol, a fungal metabolite, was synthesized in a single reaction starting from nerolidol.
Synthesis and stereochemistry of cyclonerodiol
✍ Scribed by Shigeo Nozoe; Masami Goi; Naoko Morisaki
- Publisher
- Elsevier Science
- Year
- 1971
- Tongue
- French
- Weight
- 124 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
In memory of
## Abstract 1,3‐Dipolar cycloaddition of (__E__)‐ and (__Z__)‐arylidene‐1‐tetralone derivatives affords __trans__‐ and __cis__‐spiro‐1‐pyrazolines, respectively, regio‐ and stereo‐selectively in a one‐step reaction. These rearrange into spiro‐2‐pyrazolines on proton catalysis. The relative configur