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Synthesis and spasmolytic action of 2-substituted thienopyrimidin-4-one derivatives

✍ Scribed by Natale Alfredo Santagati; Orazio Prezzavento; Ennio Bousquet; Giuseppe Ronsisvalle; Santi Spampinato

Book ID
111768935
Publisher
Pharmaceutical Press
Year
2002
Tongue
English
Weight
303 KB
Volume
54
Category
Article
ISSN
2042-7158

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## Abstract A versatile synthetic method for preparing 4‐hydroxyquinolone and 2‐substituted quinolone compounds from simple benzoic acid derivatives was demonstrated. The synthetic strategies involve the use of well known ethyl acetoacetate synthesis, malonic ester synthesis and reductive cyclizati