Optically pure trifluoromethylated imidazolidine, oxazolidine, and thiazolidine derivatives were synthesized through double Michael addition of chiral amino amides, amino acids, or amino alcohols to an easily available trifluoromethyl building block methyl (Z)-2-bromo-4,4,4-trifluoro-2-butenoate. Th
β¦ LIBER β¦
Synthesis and Semiempirical Calculations of Isatylidine, Thioisatylidine and Acenaphthylidine Derivatives of Imidazolidine, Thiazolidine, Oxazolidine and Pyrimidinetrione.
β Scribed by R. T. Pardasani; P. Pardasani; B. Gupta; A. V. Londhe; S. Kohli
- Book ID
- 101982082
- Publisher
- John Wiley and Sons
- Year
- 2005
- Weight
- 19 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0931-7597
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## Abstract magnified image The hitherto unknown 5β(2βarylβ2βoxoethyl)β4βoxoβ1,3βthiazolidines **1aβl** have been synthesized __via__cycloaddition process between thiourea and/or its derivatives with 3βaroylpropenoic acids. ^1^H NMR spectra revealed the presence of **1aβc** as a tautmeric mixture.
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