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Synthesis and screening of substituted 1,4-naphthoquinones (NPQs) as antifilarial agents

โœ Scribed by Nisha Mathew; Twinkle Karunan; Lakshmy Srinivasan; Kalyanasundaram Muthuswamy


Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
150 KB
Volume
71
Category
Article
ISSN
0272-4391

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Synthesis of 2,3-Disubstituted 1,4-Napht
โœ Jin-Cherng Lien; Chi-Rei Wu; Mann-Jen Hour; Li-Jiau Huang; Tur-Fu Huang; Sheng-C ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 605 KB

## Abstract In continuing search for novel antiplatelet agents, the highly potent agent 2โ€chloroโ€3โ€methoxycarbonylethylcarboxamidoโ€1,4โ€naphthoquinone **2** was selected as lead compound. Structureโ€activity relationships in this series were examined. Some of these compounds showed significant antipl