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Synthesis and screening of potential antimalarial agent α-(2-piperidyl)-2-(1-adamantyl)-6,8-dichloro-4-quinolinemethanol hydrochloride

✍ Scribed by Jaroslav Novotny; Carol H. Collins; Fred W. Starks

Book ID
102403623
Publisher
John Wiley and Sons
Year
1974
Tongue
English
Weight
419 KB
Volume
63
Category
Article
ISSN
0022-3549

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📜 SIMILAR VOLUMES

14C-labeled antimalarials. I. Synthesis
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✍ William H. Yanko; George F. Deebel 📂 Article 📅 1980 🏛 John Wiley and Sons 🌐 French ⚖ 291 KB

## Abstract Erythro‐ and threo‐ isomers of α‐(2‐piperidyl)‐2,8‐bis‐(triflucoromethyl)‐4‐quinolinemethanol‐α‐^14^C hydrochloride and methanesulfonate were prepared from labeled carbon dioxide for metabolic and pharmacological studies. Intermediates were 2,8‐bis(trifluoromethyl) cinchoninic‐carboxy‐^

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