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Synthesis and ring-chain isomerism of acid chlorides and amides of 2-(2-pyridyl and 2-quinolylcarbonyl) benzoic acids

✍ Scribed by G. A. Karlivan; A. É. Batse; R. É Valter


Book ID
105103777
Publisher
Springer US
Year
1994
Tongue
English
Weight
548 KB
Volume
30
Category
Article
ISSN
0009-3122

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Synthesis and metallation of 2-(pyridyl)
✍ Anne-Sophie Rebstock; Florence Mongin; François Trécourt; Guy Quéguiner 📂 Article 📅 2003 🏛 Elsevier Science 🌐 French ⚖ 155 KB

The ring deprotonation of 2-(2-and 4-pyridyl)benzoic acids using lithium dialkylamides in THF at rt, and the in situ cyclization afforded 4-and 2-azafluorenones, respectively. 1-Azafluorenone was obtained from ethyl 2-(3-pyridyl)benzoate using a similar protocol.