Synthesis and release of neurotoxic kynurenine metabolites by human monocyte-derived macrophages
β Scribed by Alberto Chiarugi; Maura Calvani; Elena Meli; Elisabetta Traggiai; Flavio Moroni
- Book ID
- 114137480
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 343 KB
- Volume
- 120
- Category
- Article
- ISSN
- 0165-5728
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The expression of the ethanol-metabolizing cytochrome P450 (CYP2E1) in human monocyte-derived macrophages was studied at the mRNA and protein levels. The presence of mRNA was investigated by reverse transcriptase-polymerase chain reaction (RT-PCR) and protein by immunocytochemistry. The data show th
## Abstract We have infected tenβdayβold primary cultures of human monocyteβderived macrophages (MDM) with HIVβ1 by cocultivation with chronically infected monocytic cell lines. This work has involved the Uβ937 monocytoid cell line, chronically infected with the HIVβIII~B~ strain of HIVβ1 (Uβ937~HI
## Abstract Macrophages are critical cells in mediating the pathology of neurodegenerative disorders and enhancement of neuronal outward potassium (K^+^) current has implicated in neuronal apoptosis. To understand how activated macrophages induce neuronal dysfunction and injury, we studied the effe