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Synthesis and Reactivity of 1,2-Dioxolanes from β,γ-Epoxy Ketones

✍ Scribed by Kandur, Wynne V.; Richert, Kathleen J.; Rieder, Curtis J.; Thomas, Andrew M.; Hu, Chunhua; Ziller, Joseph W.; Woerpel, K. A.


Book ID
121883829
Publisher
American Chemical Society
Year
2014
Tongue
English
Weight
390 KB
Volume
16
Category
Article
ISSN
1523-7060

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Synthesis and reactivity of endocyclic α
✍ Robert K. Boeckman Jr; Edward W. Thomas 📂 Article 📅 1976 🏛 Elsevier Science 🌐 French ⚖ 274 KB

h the course of our studies toward the total synthesis of the fungal metabolite Cerulenin ($1 we required 01, ,%epoxy 7' lactone (2) as a key intermediate. \_\_ A review of the literature revealed that endocyclic Cr, fl-epoxylactones such as 2 had not been prepared previously. This class of substanc