Synthesis and Reactions of 7-Fluoro-4-methyl-6-nitro-2-oxo-2 H -1-benzopyran-3-carboxylic Acid: A Novel Scaffold for Combinatorial Synthesis of Coumarins
β Scribed by Song, Aimin; Zhang, Jinhua; Lam, Kit S.
- Book ID
- 125953429
- Publisher
- American Chemical Society
- Year
- 2004
- Tongue
- English
- Weight
- 137 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1520-4766
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I211 Genbve 4 (5. V .86) ~ Comparative results on the reduction of 4,6,7,8-tetrahydro-7,7-dimethyl-2H-1 -benzopyran-2,5(3H)-diones 1 are reported. Hydride reduction (LiAIH, in EtzO or NaBH, in i-PrOH) affords 2,3,4,6,7,8-hexahydro-5H-l-benzopyran-5-ones 5 in 30-60 % isolated yield. Photochemical red