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Synthesis and reactions of 5-bromoskatole and 5-bromo-1,3-dimethylindole

✍ Scribed by Noland, Wayland E.; Reich, Charles

Book ID
120433509
Publisher
American Chemical Society
Year
1967
Tongue
English
Weight
823 KB
Volume
32
Category
Article
ISSN
0022-3263

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Nucleophilic substitution of 5-bromotriazoloisoquinoline (3) and of 7-bromo-3-methyltriazolopyridine (6) proceeds readily to give a range of 5-substituted triazoloisoquinolines (4a)-(4e), and of 7-substituted triazolopyridines (7a)-(7h) respectively. Triazoloisoquinolines have been converted into 1,