A simple, high-yielding synthesis of 2-vinyl-3H-quinazolin-4-one, 2-(1-chlorovinyl)-3H-quinazolin-4-one and 2-(1-bromovinyl)-3H-quinazolin-4-one. The 2-vinylquinazolinones 11a and 14 participate readily in nucleophilic addition reactions. Treatment with both carbon and nitrogen nucleophiles results
โฆ LIBER โฆ
Synthesis and reactions of 2-chloro-3,4-dihydrothienopyrimidines and -quinazolines
โ Scribed by Hitoshi Yamaguchi; Fumiyoshi Ishikawa
- Book ID
- 112126296
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 1981
- Tongue
- English
- Weight
- 276 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0022-152X
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## Abstract magnified image The total synthesis of chromeno[4,3,2โ__de__]quinazolinโ2โones, โquinazolines and โpyrrolo[2,1โ__b__]quinazolines from easily prepared 4โmethoxyโ1โnitroโ9__H__โxanthenโ9โone is reported. These compounds, in which a 1,3โdiazine ring is fused to the xanthene scaffold, wer
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