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Synthesis and radical polymerization behavior of a novel methacrylate with an L-leucyl-L-alanylglycine peptide moiety

✍ Scribed by Hironobu Murata; Fumio Sanda; Takeshi Endo

Publisher: John Wiley and Sons
Year: 1997
Tongue: English
Weight: 498 KB
Volume: 198
Category: Article
ISSN: 1022-1352
DOI: 10.1002/macp.1997.021980813

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✦ Synopsis

Abstract

The synthesis and radical polymerization behavior of a novel methacrylate having a peptide moiety, N‐benzyloxycarbonyl‐L‐leucyl‐L‐alanylglycine 2‐methacryloyloxyethyl ester (1), are described. 1 shows radical polymerizability in spite of the bulky peptide moiety. Only the ester group near the peptide moiety of poly(1) could be hydrolyzed selectively and completely in the hydrolysis of poly(1) in an alkaline solution.

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