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Synthesis and purification of biologically active rat brain-derived neurotrophic factor from Escherichia coli

✍ Scribed by Alessandro Negro; Vincenza Corsa; Carlo Moretto; Stephen D. Skaper; Lanfranco Callegaro


Book ID
117055755
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
513 KB
Volume
186
Category
Article
ISSN
0006-291X

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Expression of neurotrophins in pure microglia cultured from embryonic rat brain and the effects of lipopolysaccharide (LPS) on the expression were investigated. In untreated cultures, nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), and neurotrophin (NT)-4/5 mRNAs were detected b