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Synthesis and purification of a toxin-linked conjugate targeting epidermal growth factor receptor in Escherichia coli

โœ Scribed by Chengyuan Ma; Yang Li; Zhixin Li; Haiyan Huang; Kan Xu; Haiyang Xu; Jieying Bai; Xiao Li; Gang Zhao


Book ID
116829475
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
725 KB
Volume
83
Category
Article
ISSN
1046-5928

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Epidermal growth factor receptor express
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## Abstract Cervical cancer is the second most common cancer in women worldwide. Targeting the epidermal growth factor receptor (EGFR) is a very promising approach since it is overexpressed in about 90% of cervical tumors. Here, we quantified the toxic effect of SE, a targeted toxin consisting of e