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Synthesis and psychotropic properties of furyl- and thienyl-germatranes

✍ Scribed by Edmunds Lukevics; Lubov Ignatovich; Natalia Porsiurova; Skaidrīte Ǧērmane


Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
412 KB
Volume
2
Category
Article
ISSN
0268-2605

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✍ Franz Effenberger; Joachim Eichhorn 📂 Article 📅 1997 🏛 Elsevier Science 🌐 English ⚖ 503 KB

The stereoselective syntheses of thienyl and furyl analogues of ephedrine starting from (R)-and (S)-cyanohydrins, respectively, are described. Addition of methyl Grignard to the O-trimethylsilyl protected optically active cyanohydrins (R)-and (S)-3 and hydrogenation of the resulting imino intermedia