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Synthesis and properties of S,S-diaryl nucleoside phosphorodithioates in oligonucleotide synthesis

✍ Scribed by Sekine, Mitsuo; Hamaoki, Ken; Hata, Tsujiaki


Book ID
126873986
Publisher
American Chemical Society
Year
1979
Tongue
English
Weight
325 KB
Volume
44
Category
Article
ISSN
0022-3263

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Synthesis and Properties of Oligonucleot
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## Abstract Cyclohexyl nucleosides with an adenine and uracil base have been synthesized from 2‐azidocyclohexane‐1,5‐diol. The obtained racemic nucleosides were resolved using (__R__)‐__O__‐methylmandelic acid. Short oligonucleotides were synthesized using phorphoramidite chemistry. However, these