𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis and properties of some 2,3-disubstituted 6-fluoro-7-(4-methyl-1-piperazinyl)quinoxalines

✍ Scribed by Raid J. Abdel-Jalil; Raed A. Al-Qawasmeh; Wolfgang Voelter; Peter Heeg; Mustafa M. El-Abadelah; Salim S. Sabri


Publisher
Journal of Heterocyclic Chemistry
Year
2000
Tongue
English
Weight
182 KB
Volume
37
Category
Article
ISSN
0022-152X

No coin nor oath required. For personal study only.

✦ Synopsis


Abstract

The 2,3‐disubstituted 6‐fluoro‐7‐(4‐methyl‐1‐piperazinyl)‐quinoxalines (3–11) were synthesized for bioassay via reaction of 1.2‐diamino‐4‐fluoro‐5‐(4‐methyl‐1‐piperazinyl)benzene (2) with the appropriate 1,2‐dicarbonyl compounds. However, none of the tested compounds 3–11 showed significant in vitro activ ity against E. coli ATCC11229, S. aureus ATCC6538 and C.albicans SATCC10231.


📜 SIMILAR VOLUMES


ChemInform Abstract: Synthesis and Prope
✍ Raid J. Abdel-Jalil; Raed A. Al-Qawasmeh; Wolfgang Voelter; Peter Heeg; Mustafa 📂 Article 📅 2001 🏛 John Wiley and Sons ⚖ 29 KB 👁 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v

Synthesis, structures of some unsymmetri
✍ Wei-Xiao Hu; Feng Xu 📂 Article 📅 2008 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 337 KB 👁 1 views

## Abstract magnified image A series of new unsymmetrical 3‐phenyl‐6‐benzyl‐1,2,4,5‐tetrazine derivatives **10a‐i** were synthesized and characterized by IR, NMR, MS, and element analysis. The structures of **4a, 10c, 10d** and **10h** were analyzed by X‐ray crystallography, which had intermolecul