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Synthesis and Properties of Oligonucleotides Having a Phosphorus Chiral Center by Incorporation of Conformationally Rigid 5‘-Cyclouridylic Acid Derivatives

✍ Scribed by Sekine, Mitsuo; Kurasawa, Osamu; Shohda, Koh-ichiroh; Seio, Kohji; Wada, Takeshi


Book ID
126130570
Publisher
American Chemical Society
Year
2000
Tongue
English
Weight
362 KB
Volume
65
Category
Article
ISSN
0022-3263

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## Synthesis and Properties of Conformationally Rigid Cyclouridylic Acids Having Covalent Bonding Linkers Between the Uracil 5-Position and the 5'-Phosphate Group. -The cyclouridylic acid derivatives (IV) and (IX) have predominantly the ribose pucker of C3'-endo and the g+ orientation around the