Synthesis and properties of novel pyrazolopyrimidine derivatives containing sulfur atom

✍ Scribed by Hong-Qing Wang; Ming-Wu Ding; Zhao-Jie Liu

• Publisher: John Wiley and Sons
• Year: 2004
• Tongue: English
• Weight: 86 KB
• Volume: 15
• Category: Article
• ISSN: 1042-7163
• DOI: 10.1002/hc.20024

✦ Synopsis

Abstract

A series of new pyrazolopyrimidine derivatives containing sulfur atom 5 has been designed and synthesized by treatment of carbodiimide 3, which came from iminophosphorane 2 undergoing a aza‐Wittig reaction with phenyl ioscyanate, with alkylamine. The structures of compounds 5 were confirmed by ^1^H NMR, IR, EI‐mass spectroscopy, and elemental analysis. The results of preliminary bioassay indicate that most compounds 5 exhibit an inhibition effect against Cercospora beticola, Botryosphaeria berengeriana, and Pellicularia sasakii, and compound 5g shows 91.2% inhibitory rate to root of rape and the other less than 50% at 100 mg/l. © 2004 Wiley Periodicals, Inc. Heteroatom Chem 15:333–337, 2004; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20024