Synthesis and properties of nitro derivatives of 2-tert-butyl- and 2,7-di-tert-butylpyrene
β Scribed by L. Rodenburg; R. Brandsma; C. Tintel; J. van Thuijl; J. Lugtenburg; J. Cornelisse
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 580 KB
- Volume
- 105
- Category
- Article
- ISSN
- 0165-0513
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## Abstract Convenient procedures for the synthesis of 2,6βdiβtertβbutylβ4βmethylphenol (ionol) monoβ, diβ, and triphosphorus derivatives, starting from the readily accessible 3,5βdiβtertβbutylβ4βhydroxybenzaldehyde, are proposed, and some properties of the obtained compounds are presented. Β© 2008
trrf-Butyl and 2,6-di(tert-butyl)-4-methylphenyl (RHT) cyclopropanecarboxylates (4, 6, 24, 25) are lithiated with LiN(i-Pr), and t -BuLi, respectively. Reactions with alkyl halides, aldehydes, acyl chlorides, and heteroelectrophiles give a-substituted BHT esters which can be cleaved (t-BuOK/H,O/THF)