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Synthesis and Properties of New Nucleotide Analogues Possessing Squaramide Moieties as New Phosphate Isosters

✍ Scribed by Kohji Seio; Takuhei Miyashita; Kousuke Sato; Mitsuo Sekine


Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
169 KB
Volume
2005
Category
Article
ISSN
1434-193X

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## Abstract A series of new fluorescing 8‐(6‐hydroxyhexyl)isoalloxazine (=8‐(6‐hydroxyhexyl)benzo[__g__]pteridine‐2,4(1__H__,3__H__)‐dione) derivatives **4**–**13** were synthesized from 6‐[(6‐hydroxyhexyl)amino]uracil (**2**) with 1‐chloro‐4‐nitrosobenzene __via__ 8‐chloro‐10‐(6‐hydroxyhexyl)isoal