Osmium-labeled Polynucleotides: Reaction
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Luigi G. Marzilli; Brian F. Hanson; Leilani Kapili; Seth D. Rose; Michael Beer
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Article
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1978
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Elsevier Science
β 281 KB
Osmium tetraoxide, in the presence of ligands such as pyridine and bipyridine, adds across the etheno bridge of 1,N6-etheno-9-methyladenine and poly-1,N6-ethenoadenylic acid. The Os:P ratio in the labeled polynucleotide was approximately equal to 1 when bipyridine was used as the stabilizing ligand.