Synthesis and properties of 1, 2-benzodithiins
β Scribed by Werner Schroth; Hartwig Jordan; Roland Spitzner
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- French
- Weight
- 305 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
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Reaction of 2-(l-hydroxyalkyll-1,3-bensodithioles (1) with thionyl chloridetriethylamine gives high yields of 2-alkylidene-3-substituted benzodithians, and 2,3-substituted benzodithiins on treatment with acid.
## Abstract 1,4βDihydroβ1,4βdiphenylβ2,3βbenzodithiin (**3**), synthesized from 1,2βbis(phenylmethyl)benzene (**1**), was subjected to oxidation to give 1,4βdihydroβ1,4βdiphenylβ2,3βbenzodithiin 2βoxide (**4**) as a mixture of diastereomers separable by column chromatography. (1R\*,2R\*,4S\*)β1,4βD
The reaction of 3-chloropropenyl alkyl ketones or 2,3-dichloropropyl alkyl ketones with 2-substituted ethylamine derivatives leads to the formation of the hitherto unknown 1-(2-R-ethyl )-2-alkylpyrroles.