1 -( truns-[ 1Z3I ]Iodopropen-3-yl)-4-(4-cyanophenoxymethyl)pipidine has been prepared as a novel sigma receptor ligand for SPECT. This ligand was found lo be selective in v i m for the sigma receptor site (&(a) = 21.7 nM) when tested in a variety of neuroreceptor binding assays. The lipophilicity o
Synthesis and preliminary evaluation of [123I]1-(4-cyanobenzyl)-4-[[(trans-iodopropen-2-yl)oxy]-methyl]piperidine: A novel high affinity sigma receptor radioligand for SPECT
β Scribed by Rikki N. Waterhouse; Karine Mardon; Joanne C. O'Brien
- Book ID
- 117688114
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 722 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0969-8051
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