Synthesis and physical properties of substituted 4-dimethylaminomethyl-1-phenyl-1-nonen-3-ones possessing antitumor properties
β Scribed by J. R. Dimmock; W. G. Taylor
- Publisher
- John Wiley and Sons
- Year
- 1974
- Tongue
- English
- Weight
- 631 KB
- Volume
- 63
- Category
- Article
- ISSN
- 0022-3549
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β¦ Synopsis
Substituted 4-dimethylaminomethy1-l-phenyl-lnonen-3-ones were synthesized using the Mannich reaction. The spectral properties and elimination reactions of some prepared compounds were examined. Evidence is presented that the product obtained from the Mannich reaction using 1-@-dimethylaminophenyl)-l-nonen-3-one underwent aromatic rather than alkyl side-chain substitution.
Keyphrases 0 4-Dimethylaminomethy1-l-phenyl-l-nonen-3-ones, * A complete listing of the mass spectral peaks for IV is available from the authors.
π SIMILAR VOLUMES
## Abstract The reaction of phenylacetylenes 4aβh with copper(I) acetate (5) and TCNE (tetracyanoethylene) in THF/acetonitrile gave 4βphenylβ1βbutenβ3βyneβ1,1,2βtricarbonitriles 6aβh. 4i did not react to give 6i. The phenylacetylenes 4bβi were prepared by a twoβstep synthesis starting from the corr