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Synthesis and pharmacological studies of N-[4-[2-hydroxy-3-[[2-[4-(1H-imidazol-1-yl)phenoxy]ethyl]amino]propoxy]phenyl]methanesulfonamide, a novel antiarrhythmic agent with class II and class III activities

✍ Scribed by Morgan, Thomas K.; Lis, Randall; Lumma, William C.; Wohl, Ronald A.; Nickisch, Klaus; Phillips, Gary B.; Lind, Joan M.; Lampe, John W.; Di Meo, Susan V.


Book ID
118002109
Publisher
American Chemical Society
Year
1990
Tongue
English
Weight
539 KB
Volume
33
Category
Article
ISSN
0022-2623

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Synthesis and pharmacological investigat
✍ V. Alagarsamy; P. Parthiban; V. Raja Solomon; K. Dhanabal; S. Murugesan; G. Sara 📂 Article 📅 2008 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 312 KB

## Abstract magnified image A series of novel 4‐(4‐ethylphenyl)‐1‐substituted‐4__H__‐[1,2,4]triazolo[4,3‐__a__]quinazolin‐5‐ones were synthesized by the cyclization of 2‐hydrazino intermediate with various electrophile. The starting material 2‐hydrazino compound was synthesized from 2‐ethyl anilin