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Synthesis and Pharmacological Screening of Novel meso -Substituted Porphyrin Analogs

✍ Scribed by Fadda, Ahmed A.; El-Mekawy, Rasha E.; El-Shafei, Ahmed I.; Freeman, Harold

Book ID
118752596
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
322 KB
Volume
346
Category
Article
ISSN
0365-6233

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✍ Dong-Fang Shi; Richard T. Wheelhouse πŸ“‚ Article πŸ“… 2002 πŸ› Elsevier Science 🌐 French βš– 76 KB

A new method for the synthesis of meso-substituted porphyrins is described: reaction of 5,10,15,20-tetrabromoporphine magnesium complex with aryl or heteroaryl boronic acids in the presence of Pd(PPh 3 ) 4 gave meso-substituted porphyrins in yields up to 70%.