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Synthesis and Pharmacological Properties of (E)-9-Oxodec-2-enoic Acid (I).

✍ Scribed by G. Yu. Ishmuratov; A. F. Ismagilova; A. A. Sharipov; O. N. Gerasyuta; R. Ya. Kharisov; N. M. Ishmuratova; G. A. Tolstikov


Publisher
John Wiley and Sons
Year
2003
Weight
54 KB
Volume
34
Category
Article
ISSN
0931-7597

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## Abstract The synthesis of highly enriched C‐2 deuteriated and tritiated (E)‐5‐succinimido‐4‐oxo‐pent‐2‐enoic acid for use in enzymatic reduction is described. The starting materials 3‐methoxycarbonyl‐[3‐^2^H]propionyl chloride and 3‐methoxycarbonyl‐[3‐^3^H]propionyl chloride were prepared in hig