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Synthesis and Pharmacological Evaluation of Phenylethynyl[1,2,4]methyltriazines as Analogues of 3-Methyl-6-(phenylethynyl)pyridine

✍ Scribed by Carroll, F. Ivy; Kotturi, Sharadsrikar V.; Navarro, Hernán A.; Mascarella, S. Wayne; Gilmour, Brian P.; Smith, Forrest L.; Gabra, Bichoy H.; Dewey, William L.


Book ID
121247099
Publisher
American Chemical Society
Year
2007
Tongue
English
Weight
62 KB
Volume
50
Category
Article
ISSN
0022-2623

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## Abstract magnified image A series of propargylic alcohol was synthesized by the addition of phenylacetylene to isatin and its N‐substituted derivatives for the first time. This reaction involves activation of zinc reagent __via__ coordination with carbonyl substrates that behave “ligand like.”