The joint type of hybrid molecules composed of two pharmacophore moieties taken from histamine H2 and gastrin receptor antagonists have been designed and synthesized to exhibit dual histamine H2 and gastrin receptor antagonistic activities. Here we report the importance of spacers as well as binding
โฆ LIBER โฆ
Synthesis and pharmacological evaluation of highly potent dual histamine H2 and gastrin receptor antagonists
โ Scribed by Yasuyuki Kawanishi; Shoichi Ishihara; Tadahiko Tsushima; Kaoru Seno; Masanori Miyagoshi; Sanji Hagishita; Michio Ishikawa; Noriko Shima; Mayumi Shimamura; Yasunobu Ishihara
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 260 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0960-894X
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