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Synthesis and pharmacological activity of bis-diethylaminoethyl esters of 2-methyl-3-carboxyindolyl-5-hydroxyacetic acids

โœ Scribed by A. N. Grinev; A. K. Chizhov; M. D. Mashkovskii; G. Ya. Shvarts

Book ID
112407629
Publisher
Springer
Year
1978
Tongue
English
Weight
376 KB
Volume
12
Category
Article
ISSN
0091-150X

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โœ Toshio Sato; Kazuhisa Tajima; Tamotsu Fujisawa ๐Ÿ“‚ Article ๐Ÿ“… 1983 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 148 KB

The ester enolate Claisen rearrangement of IE)-and IZ)-2-butenyl ## 2-hydroxyacetates gave erythro-and threo-2-hydroxy-3-methyl-4-pentenoic acids with high diastereoselectivity via silyl ketene acetals, respect<vely.