Synthesis and PET oxidative cyclization of silyl enol ethers: build-up of quasi-steroidal carbocycles

✍ Scribed by Jens O Bunte; Stefanie Rinne; Christian Schäfer; Beate Neumann; Hans-Georg Stammler; Jochen Mattay

• Publisher: Elsevier Science
• Year: 2003
• Tongue: French
• Weight: 139 KB
• Volume: 44
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(02)02491-7

✦ Synopsis

PET oxidative cyclization of silyl enol ethers carrying suitable side chains with olefinic double bonds results in the stereoselective formation of carbocycles. Two model compounds for investigating the influence of silyl enol ether ring size are synthesized. Furthermore the synthesis of a quasi-steroidal carbocycle with an unnatural configuration is presented.